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Chemistry

Current Courses

CHEM 100 Perspectives in Environmental Chemistry

Content: General and organic chemistry concepts developed for a more thorough understanding of chemically related environmental issues such as meeting energy needs (including through nuclear energy), atmospheric pollution (the greenhouse effect, stratospheric ozone depletion, photochemical smog, acid rain), toxicology, and plastics. Lecture, laboratory.

Prerequisites: QR 101 or equivalent.

Usually offered: Annually, spring semester.

Semester credits: 5.

 

CHEM 105 Perspectives in Nutrition

Content: The fundamental basis of human nutritional needs and contemporary controversies in nutrition. Extracting energy from carbohydrates, fats, and proteins; essential amino acids and the cellular synthesis of proteins; water-soluble vitamins in major nutrient metabolism; biological function of fat-soluble vitamins; physiological roles of minerals. Readings on contemporary controversies in nutrition including the relationship between diet and disease. Lecture, laboratory.

Prerequisites: None.

Usually offered: Annually, fall semester.

Semester credits: 4.

 

CHEM 110 General Chemistry I

Content: Introduction to the general principles of chemistry required for students planning a professional career in chemistry, a related science, the health professions, or engineering. Stoichiometry, atomic structure, chemical bonding and geometry, thermochemistry, gases, types of chemical reactions, statistics. Weekly laboratory exercises emphasizing qualitative and quantitative techniques that complement the lecture material. Lecture, discussion, laboratory.

Prerequisites: QR 101 or equivalent. Previous high school chemistry not required.

Usually offered: Annually, fall semester.

Semester credits: 5.

 

CHEM 114 The Origins of Life in the Universe

Content: Processes of stellar evolution and planet formation that set the stage for life on Earth. Theories and evidence from diverse scientific disciplines on the origins of life and how physical and chemical aspects of the environment contributed to the emergence and transformations of life-forms. Scientific evaluation of the possibility of extraterrestrial life. Attention is devoted both to the processes and content of scientific discovery. Lecture, discussion, laboratory. Cross-listed with BIO 114, GEOL 114, and PHYS 114. Not applicable toward any major.

Prerequisites: QR 101 or equivalent.

Usually offered: Alternate Years, spring semester.

Semester credits: 4.

 

CHEM 120 General Chemistry II

Content: Continuation of General Chemistry I. Chemical equilibrium, kinetics, thermochemistry, thermodynamics, electrochemistry, inorganic chemistry. Weekly laboratory exercises emphasizing quantitative techniques that complement the lecture material. Lecture, discussion, laboratory.

Prerequisites: CHEM 110 or equivalent.

Usually offered: Annually, spring semester.

Semester credits: 5.

 

CHEM 210 Organic Chemistry I

Content: The basic principles of organic chemistry from a mechanistic perspective. Bonding (Lewis structures, atomic and molecular orbitals); stereochemistry (chiral compounds, enantiomers, diastereomers, conformers, optical activity, Fischer projections); nomenclature; chemistry of alkanes (free-radical substitution, reaction-coordinate energy diagrams, asymmetric induction); chemistry of alkyl halides, alcohols, ethers (substitution and elimination reactions, carbocations, pKa, nucleophilicity, leaving groups, kinetics); infrared (IR) and nuclear magnetic resonance (NMR) spectroscopy; chemistry of alkenes (addition and elimination reactions, oxidation and reduction, hydroboration, inductive and resonance effects of substituents, regio- and stereoselectivity); chemistry of alkynes (acidity, addition reactions); introduction to organometallic compounds. Lecture, discussion, laboratory.

Prerequisites: CHEM 120.

Restrictions: Sophomore standing required.

Usually offered: Annually, fall semester.

Semester credits: 5.

 

CHEM 220 Organic Chemistry II

Content: Chemistry of aldehydes and ketones (reactions at and adjacent to the carbonyl group, enolization, conjugate addition, oxidation, reduction). Lecture, conference, laboratory. Synthesis, chemistry of carboxylic acids and derivatives (pKa of acids, nucleophilic substitution of derivatives, acyl chlorides, esters, amides, anhydrides, nitriles). Carbohydrates (stereochemistry, aldoketoses, aldopentoses, aldohexoses, ketosugars, derivatives, furanose and pyranose forms, reducing and nonreducing sugars, disaccharides and polysaccharides); fats and oils; aromatic hydrocarbons (benzene, resonance and molecular orbital approaches, electrophilic and nucleophilic aromatic substitution); aromatic nitrogen and oxygen chemistry (diazotization, synthesis); chemistry of amines, amino acids, peptides, proteins, DNA; other topics. Lecture, discussion, laboratory.

Prerequisites: CHEM 210.

Restrictions: Sophomore standing required.

Usually offered: Annually, spring semester.

Semester credits: 5.

 

CHEM 244 Practicum / Internship

Content: Internship or practicum to be arranged with instructor.

Prerequisites: None.

Restrictions: Sophomore standing and consent required.

Usually offered: Annually, fall and spring semester.

Semester credits: 1-4.

 

CHEM 299 Independent Study

Content: Laboratory research or individual study topics arranged in consultation with a faculty supervisor. May be repeated for credit.

Prerequisites: None.

Restrictions: Sophomore standing and consent required.

Usually offered: Annually, fall and spring semester.

Semester credits: 1-4.

 

CHEM 310 Physical Chemistry: Thermodynamics and Kinetics

Content: Fundamental concepts of classical physical chemistry. Thermodynamics first, second, and third laws; phase equilibria; chemical equilibria; kinetics theory and practice; reaction rates.

Prerequisites: CHEM 120. PHYS 142 or PHYS 152. MATH 132.

Restrictions: Sophomore standing required.

Usually offered: Annually, spring semester.

Semester credits: 4.

 

CHEM 315 Aquatic Chemistry

Content: Principles of chemistry applied to processes governing the composition of natural waters. Focus on the solubility equilibria that control the concentration of inorganic compounds (e.g. carbonates), kinetics of mineral growth and dissolution, the role of acid-base reactions and redox equilibria.

Prerequisites: CHEM 210 (may be taken concurrently).

Restrictions: Sophomore standing required.

Usually offered: Every third year, fall semester.

Semester credits: 2.

 

CHEM 320 Physical Chemistry: Statistical Mechanics and Quantum Chemistry

Content: Statistical mechanics; quantum mechanics; quantum theory; molecular orbital theory; atomic and molecular spectroscopy; magnetic resonance spectroscopy; molecular modeling.

Prerequisites: CHEM 120. PHYS 142 or PHYS 152. MATH 132.

Restrictions: Sophomore standing required.

Usually offered: Annually, fall semester.

Semester credits: 4.

 

CHEM 330 Structural Biochemistry

Content: The structure-function relationship of biological molecules. Principles governing protein folding and methods used to assess protein structure; case studies illustrating how protein structure dictates function; DNA structure and the chemistry of protein-DNA interactions; membrane biochemistry and the dynamics of membrane organization; role of the membrane in facilitating transport, intracellular communication, and mediating the transmission of nerve signals.

Prerequisites: CHEM 220.

Restrictions: Sophomore standing required.

Usually offered: Annually, fall semester.

Semester credits: 4.

 

CHEM 335 Metabolic Biochemistry

Content: Systematic assessment of how the cell derives metabolic energy and uses the energy to drive biosynthetic reactions. Principles of thermodynamics as applied to biological transformations of energy; allosterism and enzyme reaction mechanism; metabolic regulation in guiding the flow of cellular metabolites; defects in metabolic pathways; the biochemical basis of disease.

Prerequisites: CHEM 220.

Restrictions: Sophomore standing required.

Usually offered: Annually, spring semester.

Semester credits: 4.

 

CHEM 336 Biochemistry Laboratory

Content: Contemporary biochemical techniques introduced in a project-based format. Protein production using recombinant DNA techniques; protein purification using tools such as affinity and liquid chromatography; characterization of proteins using spectroscopy and electrophoresis; functional characterization of purified proteins.

Prerequisites: CHEM 330 and CHEM 335. (CHEM 335 may be taken concurrently.)

Restrictions: Sophomore standing required.

Usually offered: Annually, spring semester.

Semester credits: 2.

 

CHEM 361 Nanomaterials Chemistry

Content: Chemical preparation and characterization of materials featuring at least one physical dimension constrained to 100 nm or less. Emphasis on applications chosen from energy, medicine, catalysis, and information storage. Emerging public understanding of nanotechnology and research into environmental health and safety impacts.

Prerequisites: CHEM 210.

Restrictions: Sophomore standing required.

Usually offered: Every third year, fall and spring semester.

Semester credits: 2.

 

CHEM 365 Physical Chemistry Laboratory

Content: Laboratory course to demonstrate the principles of physical chemistry and to develop research aptitude in chemistry. Investigation of thermochemistry, phase equilibria, kinetics, spectroscopy, and solid-state studies using techniques such as calorimetry, UV-visible, IR, NMR, mass spectroscopies, and diffraction. Attendance at departmental seminars required. Lecture, laboratory, oral presentations.

Prerequisites: CHEM 310 or CHEM 320 (may be taken concurrently).

Restrictions: Sophomore standing required.

Usually offered: Annually, spring semester.

Semester credits: 3.

 

CHEM 366 Inorganic Chemistry Laboratory

Content: Introduction to classical and modern techniques for synthesizing inorganic compounds of representative and transition metal elements and the extensive use of IR, NMR, mass, and UV-visible spectroscopies and other physical measurements to characterize products. Syntheses and characterization of inorganic and organic materials/polymers are included. Attendance at departmental seminars required. Lecture, laboratory, oral presentations.

Prerequisites: CHEM 220.

Restrictions: Sophomore standing required.

Usually offered: Annually, fall semester.

Semester credits: 3.

 

CHEM 370 Analytical Spectroscopy

Content: Survey of spectroscopic techniques used in chemical analysis, with special attention given to applications to forensic science, food science, environmental science, biochemistry, biomedicine, archaeology, art conversation, and chemical engineering.

Prerequisites: CHEM 220.

Restrictions: Sophomore standing required.

Usually offered: Every third year, spring semester.

Semester credits: 2.

 

CHEM 405 Chemistry Seminar

Content: Preparation and delivery of a seminar with accompanying abstract and bibliography. The seminar focus is either on a relevant topic in the chemical literature or, for students pursuing senior and honors research, on the thesis proposal.

Prerequisites: None.

Restrictions: Senior standing required.

Usually offered: Annually, fall and spring semester.

Semester credits: 1.

 

CHEM 420 Advanced Inorganic Chemistry

Content: Modern concepts of inorganic and transition-metal chemistry with emphasis on bonding, structure, thermodynamics, kinetics and mechanisms, and periodic and family relationships. Atomic structure, theories of bonding, symmetry, molecular shapes (point groups), crystal geometries, acid-base theories, survey of familiar elements, boron hydrides, solid-state materials, nomenclature, crystal field theory, molecular orbital theory, isomerism, geometries, magnetic and optical phenomena, spectra, synthetic methods, organometallic compounds, cage structures, clusters, lanthanides, actinides.

Prerequisites: CHEM 320.

Restrictions: Sophomore standing required.

Usually offered: Annually, spring semester.

Semester credits: 4.

 

CHEM 421 Neurochemistry

Content: Neurochemistry of synaptic transmission and an introduction to chemical approaches used to unravel the mechanistic basis of neuronal communication. Neurotransmitters, neuromodulatory proteins, and the mechanistic workings of ion channels and neuroreceptors. Neuronal processing of sensory information and intracellular signal transduction pathways. Neurochemical mechanisms that underlie memory, learning, and behavior. Behavioral sequelae that result from neurochemical abnormalities.

Prerequisites: CHEM 330 (may be taken concurrently).

Restrictions: Sophomore standing required.

Usually offered: Every third year, fall semester.

Semester credits: 2.

 

CHEM 443 Medicinal Organic Chemistry

Content: Bioorganic chemistry for selected medicinal compounds. Biophysical and chemical concepts of drug-receptor interactions and drug action. Biochemical basis for drug action elucidated in the context of fundamental organic mechanisms.

Prerequisites: CHEM 220.

Restrictions: Sophomore standing required.

Usually offered: Every third year, fall and spring semester.

Semester credits: 2.

 

CHEM 444 Internship/Practicum

Content: Internship or practicum to be arranged with instructor.

Prerequisites: None.

Restrictions: Sophomore standing required.

Usually offered: Annually, fall and spring semester.

Semester credits: 1-4.

 

CHEM 462 Advanced Organic Synthesis

Content: Chemical synthesis using the systematic “synthon” approach to design retrosynthetic pathways for complex molecules. Approaches for advanced stereochemical control. Successful synthesis routes in the primary literature examined and the experimental section of these articles interpreted to successfully bridge the gap from journal to bench.

Prerequisites: CHEM 220.

Restrictions: Sophomore standing required.

Usually offered: Every third year, spring semester.

Semester credits: 2.

 

CHEM 464 Biomolecular NMR Spectroscopy

Content: Advanced topics in nuclear magnetic resonance spectroscopy, with an emphasis on structural biology applications. Fundamental NMR theory, multidimensional methods, heteronuclear experiments, correlation spectroscopy, the nuclear Overhauser effect, chemical exchange, protein structure determination, protein dynamics.

Prerequisites: CHEM 220. CHEM 320 and/or CHEM 330 are recommended.

Restrictions: Sophomore standing required.

Usually offered: Every third year, fall and spring semester.

Semester credits: 2.

 

CHEM 480 Senior Research

Content: Experimental and/or theoretical research on an advanced topic of current significance in chemistry. Students present their thesis proposals in an early fall seminar and detail results of their investigations in a thesis in the spring. Taken for 4 semester credits each semester of the senior year. A deferred grade will be issued for the first semester of the yearlong series. When the full sequence is completed, the given grade applies to both semesters.

Prerequisites: None.

Restrictions: Senior standing and consent of instructor required.

Usually offered: Annually, fall and spring semester.

Semester credits: 4.

 

CHEM 499 Independent Research

Content: Participation in a faculty-supervised research project. Details, including academic credit, determined by the student in consultation with faculty supervisor. May be repeated for credit.

Prerequisites: Research experience.

Restrictions: Junior standing, consent of department chair, and consent of supervising faculty member required.

Usually offered: Annually, fall and spring semester.

Semester credits: 1-4.

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